The enemy within: A new pattern of antibiotic resistance
A new pattern of antibiotic resistance that is spreading around the globe may soon leave us defenseless against a frighteningly wide range of dangerous bacterial infections 
In early summer 2008 Timothy Walsh of Cardiff University in Wales got an e-mail from Christian Giske, an acquaintance who is a physician on the faculty of Sweden’s Karolinska Institute. Giske had been treating a 59-year-old man hospitalized that past January in Örebro, a small city about 100 miles from Stockholm. The man had lived with diabetes for many years, suffered several strokes and had lately developed deep bedsores. But those were not the subject of Giske’s message. Instead he was worried about a bacterium that a routine culture had unexpectedly revealed in the man’s urine. Would Walsh, who runs a lab that unravels the genetics of antibacterial resistance, be willing to take a look at the bug? Walsh agreed and put the isolate through more than a dozen assays. It was Klebsiella pneumoniae, a bacterium that in hospitalized patients is one of the most frequent causes of pneumonia and bloodstream infection. This strain, though, contained something new, a gene that Walsh had never seen before. It rendered the Klebsiella, which was already resistant to many antibiotics used in critical care medicine, insensitive to the only remaining group that worked reliably and safely–the carbapenems, the so-called drugs of last resort. The one medication the investigators found that had any effect on the resistant strain was colistin, a drug that had been out of general use for years because of its toxic effects on the kidneys. Walsh named the enzyme that this gene produced New Delhi metallo-beta-lactamase, or NDM-1, for the city where the man acquired the infection just before he returned home to Sweden. …
The Enemy Within: A New Pattern of Antibiotic Resistance (preview)
Another unexpected challenge to human well being and environmental health….
We are routinely presented with plenty of factoids, figures and statistics. Where is the scientifically-driven evidence regarding the population dynamics and unbridled, skyrocketing growth of the human species on Earth?
As humanity’s most luminous beacon of truth, science provides us with a last best hope for the survival of life as we know it on Earth. We must make certain that scientific evidence is never downplayed, distorted and denied by religious dogma, politics or ideological idiocy.
Let us not fail for another year to acknowledge extant research of human population dynamics. The willful refusal of many too many experts to assume their responsibilities to science and perform their duties to humanity could be one of the most colossal mistakes in human history. Such woefully inadequate behavior, as is evident in an incredible conspiracy of silence among experts, will soon enough be replaced with truthful expressions by those in possession of clear vision, adequate foresight, intellectual honesty and moral courage.
Hopefully leading thinkers and researchers will not continue supressing scientific evidence of human population dynamics and instead heed the words of Nobel Laureate Sir John Sulston regarding the emerging and converging, human-driven global challenges that loom ominously before humankind in our time, “we’ve got to make sure that population is recognized…. as a multiplier of many others. We’ve got to make sure that population really does peak out when we hope it will.”
Sir John goes on, “what we want to do is to see the issue of population in the open, dispassionately discussed…. and then we’ll see where it goes.”
In what is admittedly a feeble effort to help John Sulston fulfill his charge to examine all available scientific evidence regarding human population dynamics, please give careful consideration to the following presentation and then take time to rigorously scrutinize the not yet overthrown science from Russell Hopfenberg and David Pimentel regarding human population dynamics and human overpopulation. The science is clear.
http://www.panearth.org/GPSO.htm
Please accept this invitation to discern the best available science of human population dynamics and human overpopulation; discover the facts; deliberate; draw logical conclusions; and disseminate the knowledge widely.
Thank you.
Steven Earl Salmony
AWAREness Campaign on The Human Population,
established 2001
Chapel Hill, NC
http://sustainabilityscience.org/content.html?contentid=1176
http://sustainabilitysoutheast.org/